chemical moiety
IRI: https://spec.industrialontologies.org/ontology/construct/ChemicalMoiety
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: bfo:material entity
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › chemical moiety
Direct subclasses:
Definition
material entity consisting of a linked collection of atoms or a single atom and that is a proper continuant part of a molecular entity
Examples
- Fc N-glycan; Phosphate group on serine; Ubiquitin moiety; PEG chain on therapeutic protein; Carboxylate group; Methyl group
Counter-Examples
- Free‐standing molecules (e.g., methane, water); Unbound ions or radicals not attached to a larger entity
Adapted From
- http://purl.obolibrary.org/obo/CHEBI_24433
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
This term is expected to remain primitive.
Formal Axioms
First-Order Logic Axioms
ChemicalMoiety(x) → MaterialEntity(x) ∧ ∃y (properContinuantPartOfAtAllTimes(x, y) ∧ MolecularEntity(y))
Semi-Formal Natural Language Axioms
if x is a ‘chemical moiety’ then x is a ‘material entity’ and x is a ‘proper continuant part of at all times’ some ‘molecular entity’
Description Logic
constr:ChemicalMoiety ⊑ bfo:material_entity
constr:ChemicalMoiety ⊑ ∃ bfo:proper_continuant_part_of_at_all_times .constr:MolecularEntity
SubClassOf: bfo:material_entity
SubClassOf: bfo:proper_continuant_part_of_at_all_times some constr:MolecularEntity