protective agent role

IRI: https://spec.industrialontologies.org/ontology/construct/ProtectiveAgentRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › protective agent role

Direct subclasses:

• cryoprotective agent role
• shear protective agent role

Definition

role of a material entity when it is used or planned to be used to protect one or more other material entities from stress or damage

Explanatory Notes

Covers protection from physical, mechanical, thermal, chemical, or radiative stress. Subclasses are defined by the stressor type, for example cryoprotective agent role and shear protective agent role. This notion is distinct from clinical “protective agents” used to prevent disease or treat poisoning and should not be mapped to CHEBI:50267.

Examples

• role borne by Dimethyl sulfoxide (DMSO) added to freezing medium for cell preservation; role borne by Poloxamer 188 (Pluronic F-68) that is a surface-active nonionic polymer used in cell culture media to reduce shear stress from agitation and sparging

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

ProtectiveAgentRole(x) → Role(x) ∧ ∃m (MaterialEntity(m) ∧ roleOf(x, m))

Semi-Formal Natural Language Axioms

if x is a ‘protective agent role’ then x is a ‘role’ that is the ‘role of’ some ‘material entity’

Description Logic

constr:ProtectiveAgentRole ⊑ bfo:role

constr:ProtectiveAgentRole ⊑ ∃ constr:roleOf .bfo:material_entity

SubClassOf: bfo:role

SubClassOf: constr:roleOf some bfo:material_entity