steroid
IRI: https://spec.industrialontologies.org/ontology/construct/Steroid
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: lipid
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › molecular entity › organic molecular entity › lipid › steroid
Definition
lipid that has a core structure of four fused carbon rings, consisting of three six-membered rings and one five-membered ring
Explanatory Notes
1) Additional side chains or functional groups may be attached to the core rings, and the rings may be hydrogenated or slightly modified by rearrangement. 2) Steroids include naturally occurring compounds and synthetic analogues. This class encompasses sterols (e.g., cholesterol), bile acids, and steroid hormones, as well as numerous synthetic derivatives with medicinal applications. 3) Chemically, steroids are compounds derived from the cyclopenta[a]phenanthrene skeleton, typically with methyl groups at C-10 and C-13 and often an alkyl side chain at C-17. Natural steroids arise from squalene and may show partial hydrogenation or minor ring modifications.
Examples
- Estradiol; Testosterone; Cortisol
Adapted From
- https://www.ebi.ac.uk/chebi/CHEBI:35341
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
See the primitive rationale under molecular entity
Formal Axioms
First-Order Logic Axioms
Steroid(x) → Lipid(x)
Semi-Formal Natural Language Axioms
if x is a ‘steroid’ then x is a ‘lipid’
Description Logic
SubClassOf: constr:Lipid