input material attribute specification
IRI: https://spec.industrialontologies.org/ontology/construct/InputMaterialAttributeSpecification
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/
SubClass Of: input specification
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:generically dependent continuant › information content entity › input specification › input material attribute specification
Direct subclasses:
Definition
input specification that prescribes some quality, capability, constitution, or composition of an input material that can have an impact on process performance or on the quality of the output material
Explanatory Notes
Input materials can be raw materials, process intermediate materials, or production consumables, which is reflected in the prescription axiom
Examples
- the input material attribute specification for pH of a buffer used as an input material; the input material attribute specification for osmolality of a culture medium used as an input material; the input material attribute specification for glucose concentration in a feed medium;
Adapted From
- https://database.ich.org/sites/default/files/Q8_R2_Guideline.pdf and https://pmc.ncbi.nlm.nih.gov/articles/PMC4070262/
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
InputMaterialAttributeSpecification(x) → InputSpecification(x) ∧ ∃a (prescribes(x, a) ∧ (Quality(a) ∨ Capability(a)) ∧ ∃m (inheresIn(a, m) ∧ ((RawMaterial(m) ∨ ProcessIntermediateMaterial(m) ∨ ProductionConsumable(m)) ∨ (MaterialEntity(m) ∧ ∃w (continuantPartOfAtAllTimes(m, w) ∧ (RawMaterial(w) ∨ ProcessIntermediateMaterial(w) ∨ ProductionConsumable(w)))))))
Semi-Formal Natural Language Axioms
if x is an ‘input material attribute specification’ then x is an ‘input specification’ that ‘prescribes’ some ‘quality’ or ‘capability’ that ‘inheres in’ either some ‘raw material’, ‘process intermediate material’, or ‘production consumable’, or in some ‘material entity’ that is a ‘continuant part of at all times’ some ‘raw material’, ‘process intermediate material’, or ‘production consumable’
Description Logic
constr:InputMaterialAttributeSpecification ⊑ constr:InputSpecification
constr:InputMaterialAttributeSpecification ⊑ ∃ constr:prescribes .((bfo:quality ⊔ constr:Capability) ⊓ ∃ bfo:inheres_in .(bfo:material_entity ⊓ ∃ bfo:continuant_part_of_at_all_times .(constr:ProcessIntermediateMaterial ⊔ constr:ProductionConsumable ⊔ constr:RawMaterial))) ⊔ ∃ constr:prescribes .((bfo:quality ⊔ constr:Capability) ⊓ ∃ bfo:inheres_in .(constr:ProcessIntermediateMaterial ⊔ constr:ProductionConsumable ⊔ constr:RawMaterial))
SubClassOf: constr:InputSpecification
SubClassOf: constr:prescribes some ((bfo:quality or constr:Capability) and bfo:inheres_in some (bfo:material_entity and bfo:continuant_part_of_at_all_times some (constr:ProcessIntermediateMaterial or constr:ProductionConsumable or constr:RawMaterial))) or constr:prescribes some ((bfo:quality or constr:Capability) and bfo:inheres_in some (constr:ProcessIntermediateMaterial or constr:ProductionConsumable or constr:RawMaterial))