cell culture doubling time

IRI: https://spec.industrialontologies.org/ontology/construct/CellCultureDoublingTime

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/

SubClass Of: bfo:temporal interval

Class Hierarchy

owl:Thing › bfo:entity › bfo:occurrent › bfo:temporal region › bfo:one-dimensional temporal region › bfo:temporal interval › cell culture doubling time

Definition

temporal interval over which the size of a cell population doubles

Examples

• the cell culture doubling time of a CHO cell population during seed train expansion; the cell culture doubling time calculated from viable cell density measurements during exponential growth; the cell culture doubling time of an E. coli culture during fermentation;

Adapted From

• http://purl.obolibrary.org/obo/MSIO_0000061

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create necessary and sufficient conditions.

Formal Axioms

First-Order Logic Axioms

CellCultureDoublingTime(x) → TemporalInterval(x)

Semi-Formal Natural Language Axioms

if x is a ‘cell culture doubling time’ then x is a ‘temporal interval’

Description Logic

constr:CellCultureDoublingTime ⊑ bfo:temporal_interval

SubClassOf: bfo:temporal_interval