input critical material attribute specification
IRI: https://spec.industrialontologies.org/ontology/construct/InputCriticalMaterialAttributeSpecification
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/
SubClass Of: input material attribute specification
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:generically dependent continuant › information content entity › input specification › input material attribute specification › input critical material attribute specification
Definition
input material attribute specification that prescribes some quality, capability, constitution, or composition whose variation can have a significant impact on the quality of the output material
Examples
- the CMA specification for manganese concentration in a chemically defined medium when variation in manganese concentration can affect glycosylation of the output material; the CMA specification for glucose concentration in a feed medium when variation in glucose concentration can affect glycan profile of the output material; the CMA specification for culture medium osmolality when variation in osmolality can affect charge variant profile or aggregation level of the output material;
Adapted From
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4070262/
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
InputCriticalMaterialAttributeSpecification(x) → InputMaterialAttributeSpecification(x)
Semi-Formal Natural Language Axioms
if x is an ‘input critical material attribute specification’ then x is an ‘input material attribute specification’